The Seven Tests

Your Blood

Gaucher disease can affect your blood in a variety of ways:

  • In Gaucher disease, the spleen becomes enlarged and overactive, breaking down too many red blood cells. This leads to anemia. Anemia can make you feel fatigued. People often describe feeling tired or weak, being breathless or lacking energy.
  • An overactive spleen can reduce blood platelets. This can make it harder for your blood to clot. For this reason, you might bruise and bleed easily. This can happen especially after an injury, surgery, biopsy, dental work or childbirth.
  • An overactive spleen lessens the number of available white blood cells. These cells help your body fight infection. Fewer white blood cells may lead to more infections.

Test 4: Hemoglobin test

This blood test measures the total amount of hemoglobin in your blood. Hemoglobin, a part of red blood cells, carries oxygen. A low hemoglobin level is a sign of anemia, which results in fatigue.

Test 5: Platelet count

This blood test measures the number of platelets in the blood. Platelets are needed for clotting blood. A low platelet count may cause bruising and bleeding.

Test 6: Biochemical evaluations

These are special blood tests that can detect subtle changes in the disease and are useful for some patients. They can help check your progress toward achieving your treatment goals. Among the markers your healthcare providers may check are:

  • Chitotriosidase
  • Angiotensin-converting enzyme (ACE)
  • Tartrate-resisitant acid phosphatase (TRAP)

Learn more about monitoring tests for your liver and spleen.